LigoFlex Gel

Summary

Rheumatoid arthritis is a chronic autoimmune inflammatory disease that presents as a symmetrical polyarthritis characterised by joint pain, swelling, and stiffness. It can affect any synovial joint in the body, most commonly starting in the small joints of the hands and feet, with the potential to impact every aspect of daily living. High levels of inflammation are associated with fatigue and impairment of participation in occupational, recreational, and societal roles. Rheumatoid arthritis can affect men, women, and children at any age, but is 2–3 times more likely to occur in women and is more common with increasing age, with onset most often occurring at 60–70 years of age. Without adequate treatment, the disease can lead to progressive joint destruction and deformity, causing long-term disability, chronic pain, and premature death. (Reference: Global, regional, and national burden of rheumatoid arthritis, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021; GBD 2021 Rheumatoid Arthritis Collaborators* ) .

Ingredients

  • Vitex negundo
  • Curcuma Longa
  • Capsicum oleoresin
  • Wintergreen oil
  • Withania somnifera

$26.00

Product Details

Description

ES-LigoFlex , a combination of natural bioceutical (plant bioactives) COX-2 inhibitor formulation that blocks the action of COX-2 enzymes, which help reduce inflammation and pain. Promotes analgesic anti-inflammatory activities that reduce joint discomfort, increase knee flexion and mobility associated with rheumatoid /osteo-arthritic conditions. 
Fast-acting anti-inflammatory, deep penetrating and long-lasting relief of arthritic and joint pain.

Research And Publications

Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study

R R Kulkarni 1, P S Patki, V P Jog, S G Gandage, B Patwardhan
Affiliations Expand
PMID: 1943180 DOI: 10.1016/0378-8741(91)90167-c
Abstract:
The clinical efficacy of a herbomineral formulation containing roots of Withania somnifera, the stem of Boswellia serrata, rhizomes of Curcuma longa and a zinc complex (Articulin-F), was evaluated in a randomized, double-blind, placebo controlled, cross-over study in patients with osteoarthritis. After a one-month single blind run-in period, 42 patients with osteoarthritis were randomly allocated to receive either a drug treatment or a matching placebo for a period of three months. After a 15-day wash-out period the patients were transferred to the other treatment for a further period of three months. Clinical efficacy was evaluated every fortnight on the basis of severity of pain, morning stiffness, Ritchie articular index, joint score, disability score and grip strength. Other parameters like erythrocyte sedimentation rate and radiological examination were carried out on a monthly basis. Treatment with the herbomineral formulation produced a significant drop in severity of pain (P less than 0.001) and disability score (P less than 0.05). Radiological assessment, however, did not show any significant changes in both the groups. Side effects observed with this formulation did not necessitate withdrawal of treatment.

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